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Thiazolidindions, including pioglitazon and osiglitazon, caus xacbat congstiv hat ailu in som patints Monitcaully at initiation dos incass signs and symptoms hat ailu (including xcssiv, apid wight gain; dyspna; and/dma); i ths signs symptoms dvlop, manag hat ailu accoding cunt standads ca; consid discontinuing ducing dos Not commndd in patints with symptomatic hat ailu; initiation ths dugs in patints with stablishd NYHA class III IV hat ailu is containdicatd.

Total biliubin = 45 mL/min (i G is not includd on th clinical lab pot, th chonic kidny disas pidmiology [CKD-PI] catinin calculatmay b usd) Paticipant is abl tswallow a tablt whol Paticipant is willing and abl tpaticipat th duation th study.

Many dugs can intact with mtomin and pioglitazon, making this mdicin lss ctiv incasing you isk lactic acidosis. This includs psciption and ov-th-count mdicins, vitamins, and hbal poducts. Not all possibl intactions a listd h. Tll you doctabout all you cunt mdicins and any mdicin you stat stop using.

Chck you blood suga gulaly as dictd by you docto. Kp tack th sults, and sha thm with you docto. Tll you docti you blood suga masumnts a tohigh tolow. You dosag/tatmnt may nd tb changd. It may tak up t2 t3 months bth ull bnit this dug taks ct.

Bhaving sugy any X-ay/scanning pocdu using iodinatd contast, tll you doctdntist about all th poducts you us (including psciption dugs, nonpsciption dugs, and hbal poducts). You may nd tstop this mdication a shot tim th sugy/pocdu. Ask you doctdntist instuctions byou sugy/pocdu.

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