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Table 2 describes the effects of co-administered drugs on fenofibric acid systemic exposure.
Store at room temperatureProtect from lightStore in a dry placeDo not store in a bathroomSome brands of Tricorfenofibrate and derivatives tabletsmust be stored in the original containerDo not remove the anti-moisture cube or packetTalk with your doctor or pharmacist if you are not sureKeep all drugs in a safe placeKeep all drugs out of the reach of children and petsThrow away unused or expired drugsDo not flush down a toilet order septilin sirop or pour down a drain unless you are told to do soCheck with your pharmacist if you have questions about the best way to throw out drugsThere may be drug take-back programs in your area.
Fenofibrate is a pro-drug of the active chemical moiety fenofibric acidFenofibrate is converted by ester hydrolysis in the body to fenofibric acid which is the active constituent measurable in the circulation.
The influence of race on the pharmacokinetics of fenofibrate has not been studiedhowever fenofibrate is not metabolized by enzymes known for exhibiting inter-ethnic variability.
The following adverse reactions have been identified during postapproval use of fenofibratemyalgiarhabdomyolysispancreatitisacute renal failuremuscle spasmhepatitiscirrhosisanemiaarthralgiadecreases in hemoglobindecreases in hematocritwhite blood cell decreasesastheniaand severely depressed HDL-cholesterol levelsBecause these reactions are reported voluntarily from a population of uncertain sizeit is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
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